| Gene Symbol |
BNIP3
|
| Gene Synonyms |
NIP3 |
| Gene Full Name |
BCL2 interacting protein 3 |
| Gene Summary |
This gene is encodes a mitochondrial protein that contains a BH3 domain and acts as a pro-apoptotic factor. The encoded protein interacts with anti-apoptotic proteins, including the E1B 19 kDa protein and Bcl2. This gene is silenced in tumors by DNA methylation. [provided by RefSeq, Dec 2014] |
| Molecular Weight(MW) |
28 kDa(Observed:56 kDa Homodimer) |
| Cellular Localization |
Membrane, Mitochondrion, Mitochondrion outer membrane |