WB
Western blot analysis using Cdk4 antibody against THP-1(1), K562(2) cell lysate.IHC
Immunohistochemical analysis of paraffin-embedded Human rectal cancer tissues using Cdk4 antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human breast cancer tissues using Cdk4 antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human lung cancer tissues using Cdk4 antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human renal carcinoma tissues using Cdk4 antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human kidney tissues using Cdk4 antibody with DAB staining.| Product Name | Anti-Cdk4 antibody-poly-HRP |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | poly-HRP |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:200-1:2000 IHC:1:100-1:1000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | CDK4 |
|---|---|
| Gene Synonyms | CMM3 PSK-J3 |
| Gene Full Name | cyclin dependent kinase 4 |
| Gene Summary | The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression. The activity of this kinase is restricted to the G1-S phase, which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16(INK4a). This kinase was shown to be responsible for the phosphorylation of retinoblastoma gene product (Rb). Mutations in this gene as well as in its related proteins including D-type cyclins, p16(INK4a) and Rb were all found to be associated with tumorigenesis of a variety of cancers. Multiple polyadenylation sites of this gene have been reported. [provided by RefSeq, Jul 2008] |
| Molecular Weight(MW) | 34 kDa |
| Cellular Localization | Cytoplasm, Membrane, Nucleus |
| SwissProt ID | P11802 |
|---|
WB
Western blot analysis using Cdk4 antibody against THP-1(1), K562(2) cell lysate.
IHC
Immunohistochemical analysis of paraffin-embedded Human rectal cancer tissues using Cdk4 antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human breast cancer tissues using Cdk4 antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human lung cancer tissues using Cdk4 antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human renal carcinoma tissues using Cdk4 antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human kidney tissues using Cdk4 antibody with DAB staining.| Application Notes | WB:1:200-1:2000 IHC:1:100-1:1000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide. |
