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Anti-ABCG2 antibody-poly-HRP

Catalog Number:OM642249-poly-HRP
Human;Mouse;Rat
WB;IHC
OM642249-poly-HRP
Discount Price
OM642249-poly-HRP-100ul
1~2 Week
100ul
1~2 Week
Product Profile
Product Name Anti-ABCG2 antibody-poly-HRP
Antibody Type Primary Antibodies
Immunogen Polypeptide
Conjugation poly-HRP
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WBIHC
WB:1:200-1:2000
IHC:1:100-1:1000
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol ABCG2
Gene Synonyms MRX
MXR
ABCP
BCRP
BMDP
MXR1
ABC15
BCRP1
CD338
GOUT1
MXR-1
CDw338
UAQTL1
EST157481
Gene Full Name ATP binding cassette subfamily G member 2 (Junior blood group)
Gene Summary The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
Molecular Weight(MW) 72 kDa, 67 kDa(Observed:140 kDa Homodimer)
Cellular Localization Cell membrane, Membrane, Mitochondrion
Database Links
SwissProt ID Q9UNQ0
Application

WB

Western blot analysis using ABCG2 antibody against Hela(1), A431(2), HepG2(3) cell lysate.

IHC

Immunohistochemical analysis of paraffin-embedded Human lung cancer tissues using ABCG2 antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human lung cancer tissues using ABCG2 antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human renal carcinoma tissues using ABCG2 antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human Kidney tissues using ABCG2 antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human rectal cancer tissues using ABCG2 antibody with DAB staining.
Application Notes WB:1:200-1:2000
IHC:1:100-1:1000
Additional Information
Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer Purified antibody in PBS with 0.05% sodium azide.
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