| Gene Symbol |
FOS
|
| Gene Synonyms |
AP-1 C-FOS cFos D12Rfj1 p55 |
| Gene Full Name |
Fos proto-oncogene, AP-1 transcription factor subunit |
| Gene Summary |
The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death. [provided by RefSeq, Jul 2008] |
| Alternative Names |
activator protein 1 cellular oncogene c-fos cellular oncogene fos FBJ murine osteosarcoma viral (v-fos) oncogene homolog (oncogene FOS) FBJ murine osteosarcoma viral oncogene homolog FBJ osteosarcoma oncogene FOS Fos proto-oncogene AP-1 trancription factor subunit G0/G1 switch regulatory protein 7 proto-oncogene c-Fos proto-oncogene protein c-fos transcription factor AP-1 subunit c-Fos |
| Molecular Weight(MW) |
41kDa(observed:38-70、50kDa) |
| Cellular Localization |
Cytoplasm, Endoplasmic reticulum, Nucleus |