WB
Western blot analysis using MCM3 antibody against Hela(1), Jurkat(2),HEK293(3),HepG2(4) cell lysate.IHC
Immunohistochemical analysis of paraffin-embedded Human prostate cancer tissues using MCM3 antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human Kidney tissues using MCM3 antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human breast cancer tissues using MCM3 antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human lung cancer tissues using MCM3 antibody with DAB staining.WB
Western blot analysis using MCM3 antibody against Mouse testes tissue(1).WB
Western blot analysis using GARS antibody against Rat stomach tissue(1),Rat serum tissue(2),Rat lung tissue(3).| Product Name | Anti-MCM3 antibody-HRP |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | HRP |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:200-1:2000 IHC:1:100-1:1000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | MCM3 |
|---|---|
| Gene Synonyms | HCC5 P1.h RLFB P1-MCM3 |
| Gene Full Name | minichromosome maintenance complex component 3 |
| Gene Summary | The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with and is acetylated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2018] |
| Molecular Weight(MW) | 91 kDa |
| Cellular Localization | Chromosome, Nucleus |
| SwissProt ID | P25205 |
|---|
WB
Western blot analysis using MCM3 antibody against Hela(1), Jurkat(2),HEK293(3),HepG2(4) cell lysate.
IHC
Immunohistochemical analysis of paraffin-embedded Human prostate cancer tissues using MCM3 antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human Kidney tissues using MCM3 antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human breast cancer tissues using MCM3 antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human lung cancer tissues using MCM3 antibody with DAB staining.
WB
Western blot analysis using MCM3 antibody against Mouse testes tissue(1).
WB
Western blot analysis using GARS antibody against Rat stomach tissue(1),Rat serum tissue(2),Rat lung tissue(3).| Application Notes | WB:1:200-1:2000 IHC:1:100-1:1000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide. |
