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Anti-MCM3 antibody-poly-HRP

Catalog Number:OM642309-poly-HRP
Human;Mouse;Rat
WB;IHC
OM642309-poly-HRP
Discount Price
OM642309-poly-HRP-100ul
1~2 Week
100ul
1~2 Week
Product Profile
Product Name Anti-MCM3 antibody-poly-HRP
Antibody Type Primary Antibodies
Immunogen Polypeptide
Conjugation poly-HRP
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WBIHC
WB:1:200-1:2000
IHC:1:100-1:1000
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol MCM3
Gene Synonyms HCC5
P1.h
RLFB
P1-MCM3
Gene Full Name minichromosome maintenance complex component 3
Gene Summary The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with and is acetylated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2018]
Molecular Weight(MW) 91 kDa
Cellular Localization Chromosome, Nucleus
Database Links
SwissProt ID P25205
Application

WB

Western blot analysis using MCM3 antibody against Hela(1), Jurkat(2),HEK293(3),HepG2(4) cell lysate.

IHC

Immunohistochemical analysis of paraffin-embedded Human prostate cancer tissues using MCM3 antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human Kidney tissues using MCM3 antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human breast cancer tissues using MCM3 antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human lung cancer tissues using MCM3 antibody with DAB staining.

WB

Western blot analysis using MCM3 antibody against Mouse testes tissue(1).

WB

Western blot analysis using GARS antibody against Rat stomach tissue(1),Rat serum tissue(2),Rat lung tissue(3).
Application Notes WB:1:200-1:2000
IHC:1:100-1:1000
Additional Information
Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer Purified antibody in PBS with 0.05% sodium azide.
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