| Product Name | Anti-GCLM antibody-Gold |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | Gold |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | GCLM |
|---|---|
| Gene Synonyms | Gcmc GLCLR |
| Gene Full Name | glutamate-cysteine ligase modifier subunit |
| Gene Summary | Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia. Alternative splicing results in multiple transcript variants encoding different isoforms. |
| Alternative Names | gamma glutamylcysteine synthetase gamma-ECS regulatory subunit gamma-glutamylcysteine synthetase regulatory subunit GCLM GCS light chain glutamate cysteine ligase (gamma-glutamylcysteine synthetase) regulatory glutamate-cysteine ligase (gamma-glutamylcysteine synthetase) regulatory (30.8kD) glutamate-cysteine ligase modifier subunit delta2 alternative splicing glutamate-cysteine ligase regulatory protein glutathione biosynthetic enzyme GSC light chain |
| Molecular Weight(MW) | 31kDa(obsesrved:25kDa) |
| Cellular Localization | Cytosol |
| SwissProt ID | P48507 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide,40% Glycerol. |
