WB
Western blot analysis using BRG1 antibody against Jurkat(1), COS7(2) cell lysate.IHC
Immunohistochemical analysis of paraffin-embedded Human prostate cancer tissues using BRG1 antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human esophageal tissues using BRG1 antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human rectal cancer tissues using BRG1 antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human thyroid carcinoma tissues using BRG1 antibody with DAB staining.| Product Name | Anti-BRG1 antibody-HRP |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | HRP |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:200-1:2000 IHC:1:100-1:1000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | SMARCA4 |
|---|---|
| Gene Synonyms | BRG1 CSS4 SNF2 SWI2 MRD16 RTPS2 BAF190 SNF2L4 SNF2LB hSNF2b BAF190A SNF2-beta |
| Gene Full Name | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 |
| Gene Summary | The protein encoded by this gene is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulate the expression of the tumorigenic protein CD44. Mutations in this gene cause rhabdoid tumor predisposition syndrome type 2. Multiple transcript variants encoding different isoforms have been found for this gene. |
| Molecular Weight(MW) | 185 kDa |
| Cellular Localization | Nucleus |
| SwissProt ID | P51532 |
|---|
WB
Western blot analysis using BRG1 antibody against Jurkat(1), COS7(2) cell lysate.
IHC
Immunohistochemical analysis of paraffin-embedded Human prostate cancer tissues using BRG1 antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human esophageal tissues using BRG1 antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human rectal cancer tissues using BRG1 antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human thyroid carcinoma tissues using BRG1 antibody with DAB staining.| Application Notes | WB:1:200-1:2000 IHC:1:100-1:1000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide. |
