WB
Western blot analysis using VRK1 antibody against K562(1) cell lysate.IHC
Immunohistochemical analysis of paraffin-embedded Human prostate tissues using VRK1 antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human Kidney tissues using VRK1 antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human prostate tissues using VRK1 antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human testi tissues using VRK1 antibody with DAB staining.| Product Name | Anti-VRK1 antibody-poly-HRP |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | poly-HRP |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:200-1:2000 IHC:1:100-1:1000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | VRK1 |
|---|---|
| Gene Synonyms | PCH1 PCH1A |
| Gene Full Name | VRK serine/threonine kinase 1 |
| Gene Summary | This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. This gene is widely expressed in human tissues and has increased expression in actively dividing cells, such as those in testis, thymus, fetal liver, and carcinomas. Its protein localizes to the nucleus and has been shown to promote the stability and nuclear accumulation of a transcriptionally active p53 molecule and, in vitro, to phosphorylate Thr18 of p53 and reduce p53 ubiquitination. This gene, therefore, may regulate cell proliferation. This protein also phosphorylates histone, casein, and the transcription factors ATF2 (activating transcription factor 2) and c-JUN. |
| Molecular Weight(MW) | 45 kDa |
| Cellular Localization | Cytoplasm, Cytoskeleton, Nucleus |
| SwissProt ID | Q99986 |
|---|
WB
Western blot analysis using VRK1 antibody against K562(1) cell lysate.
IHC
Immunohistochemical analysis of paraffin-embedded Human prostate tissues using VRK1 antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human Kidney tissues using VRK1 antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human prostate tissues using VRK1 antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human testi tissues using VRK1 antibody with DAB staining.| Application Notes | WB:1:200-1:2000 IHC:1:100-1:1000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide. |
