WB
Western blot analysis using ADAMTS4 antibody against MCF-7(1) cell lysate.IHC
Immunohistochemical analysis of paraffin-embedded Human breast cancer tissues using ADAMTS4 antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human rectal cancer tissues using ADAMTS4 antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human lung cancer tissues using ADAMTS4 antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human lung cancer 2 tissues using ADAMTS4 antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human breast cancer tissues using ADAMTS4 antibody with DAB staining.| Product Name | Anti-ADAMTS4 antibody-HRP |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | HRP |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:200-1:2000 IHC:1:100-1:1000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | ADAMTS4 |
|---|---|
| Gene Synonyms | ATS4 DMP-1 ADAMTS-2 ADAMTS-4 |
| Gene Full Name | ADAM metallopeptidase with thrombospondin type 1 motif 4 |
| Gene Summary | This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of this family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene lacks a C-terminal TS motif. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease is responsible for the degradation of aggrecan, a major proteoglycan of cartilage, and brevican, a brain-specific extracellular matrix protein. The expression of this gene is upregulated in arthritic disease and this may contribute to disease progression through the degradation of aggrecan. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. |
| Molecular Weight(MW) | 90 kDa |
| Cellular Localization | Extracellular matrix, Secreted |
| SwissProt ID | O75173 |
|---|
WB
Western blot analysis using ADAMTS4 antibody against MCF-7(1) cell lysate.
IHC
Immunohistochemical analysis of paraffin-embedded Human breast cancer tissues using ADAMTS4 antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human rectal cancer tissues using ADAMTS4 antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human lung cancer tissues using ADAMTS4 antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human lung cancer 2 tissues using ADAMTS4 antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human breast cancer tissues using ADAMTS4 antibody with DAB staining.| Application Notes | WB:1:200-1:2000 IHC:1:100-1:1000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide. |
