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Anti-HNMT antibody-poly-HRP

Catalog Number:OM642409-poly-HRP
Human;Mouse;Rat
WB;IHC
OM642409-poly-HRP
Discount Price
OM642409-poly-HRP-100ul
1~2 Week
100ul
1~2 Week
Product Profile
Product Name Anti-HNMT antibody-poly-HRP
Antibody Type Primary Antibodies
Immunogen Polypeptide
Conjugation poly-HRP
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WBIHC
WB:1:200-1:2000
IHC:1:100-1:1000
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol HNMT
Gene Synonyms HMT
MRT51
HNMT-S1
HNMT-S2
Gene Full Name histamine N-methyltransferase
Gene Summary In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene.
Molecular Weight(MW) 33 kDa(observed:35kDa)
Cellular Localization Cytoplasm
Database Links
SwissProt ID P50135
Application

WB

Western blot analysis using HNMT antibody against Jurkat(1),COS-7(2),MCF-7(3),A431(4) cell lysate.

IHC

Immunohistochemical analysis of paraffin-embedded Human breast cancer tissues using HNMT antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human renal carcinoma tissues using HNMT antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human breast cancer tissues using HNMT antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human lung cancer tissues using HNMT antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human rectal cancer tissues using HNMT antibody with DAB staining.

WB

Western blot analysis using HNMT antibody against Mouse testes tissue(1).
Application Notes WB:1:200-1:2000
IHC:1:100-1:1000
Additional Information
Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer Purified antibody in PBS with 0.05% sodium azide.
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