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Anti-FDPS antibody-HRP

Catalog Number:OM642413-HRP
Human;Mouse;Rat
WB;IHC
OM642413-HRP
Discount Price
OM642413-HRP-100ul
1~2 Week
100ul
1~2 Week
Product Profile
Product Name Anti-FDPS antibody-HRP
Antibody Type Primary Antibodies
Immunogen Polypeptide
Conjugation HRP
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WBIHC
WB:1:200-1:2000
IHC:1:100-1:1000
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol FDPS
Gene Synonyms FPS
FPPS
POROK9
Gene Full Name farnesyl diphosphate synthase
Gene Summary This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Multiple pseudogenes have been found on chromosomes 1, 7, 14, 15, 21 and X. Multiple transcript variants encoding different isoforms have been found for this gene.
Molecular Weight(MW) 48 kDa
Cellular Localization Cytoplasm
Database Links
SwissProt ID P14324
Application

WB

Western blot analysis using FDPS antibody against THP-1(1), HepG2(2) cell lysate.

IHC

Immunohistochemical analysis of paraffin-embedded Human prostate cancer tissues using FDPS antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human prostate cancer tissues using FDPS antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human Kidney tissues using FDPS antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human breast tissues using FDPS antibody with DAB staining.

WB

Western blot analysis using FDPS antibody against Mouse heart tissue(1),Mouse liver tissue(2).
Application Notes WB:1:200-1:2000
IHC:1:100-1:1000
Additional Information
Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer Purified antibody in PBS with 0.05% sodium azide.
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