| Gene Symbol |
SMURF2
|
| Gene Synonyms |
SMAD ubiquitination regulatory factor 2 |
| Gene Full Name |
SMAD specific E3 ubiquitin protein ligase 2 |
| Gene Summary |
Enables SMAD binding activity; identical protein binding activity; and ubiquitin-protein transferase activity. Involved in negative regulation of transforming growth factor beta receptor signaling pathway; positive regulation of trophoblast cell migration; and ubiquitin-dependent SMAD protein catabolic process. Located in nuclear speck. Part of ubiquitin ligase complex. |
| Molecular Weight(MW) |
86 kDa |
| Cellular Localization |
Cell membrane, Cytoplasm, Membrane, Nucleus |
