ICC/IF
Immunofluorescence analysis of A549 cells using ACVR1B antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.| Product Name | Anti-ACVR1B antibody-AF488 |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | AF488 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IFFC |
| IF:1:50-1:200 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | ACVR1B |
|---|---|
| Gene Synonyms | 6820432J04 ActR-IB ACTRIB ACVRLK4 ALK-4 ALK4 SKR2 |
| Gene Full Name | activin A receptor type 1B |
| Gene Summary | This gene encodes an activin A type IB receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I and two type II receptors. This protein is a type I receptor which is essential for signaling. Mutations in this gene are associated with pituitary tumors. Alternate splicing results in multiple transcript variants. |
| Alternative Names | activin A receptor type IB activin A receptor type II-like kinase 4 activin receptor type IB activin receptor-like kinase 4 ACTR-IB ACTRI ACVR1A ACVRLK2 ALK-4 ALK2 FOP Serine/threonine-protein kinase receptor R2 SKR1 TSRI |
| Molecular Weight(MW) | 57 kDa(observed：35kDa） |
| Cellular Localization | Plasma membrane |
| SwissProt ID | P36896 |
|---|
ICC/IF
Immunofluorescence analysis of A549 cells using ACVR1B antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.| Application Notes | IF:1:50-1:200 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide. |
