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Anti-HLA-F antibody-poly-HRP

Catalog Number:OM642458-poly-HRP
Human;Mouse;Rat
WB;IHC
OM642458-poly-HRP
Discount Price
OM642458-poly-HRP-100ul
1~2 Week
100ul
1~2 Week
Product Profile
Product Name Anti-HLA-F antibody-poly-HRP
Antibody Type Primary Antibodies
Immunogen Polypeptide
Conjugation poly-HRP
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WBIHC
WB:1:200-1:2000
IHC:1:100-1:1000
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol HLA-F
Gene Synonyms HLAF
CDA12
HLA-5.4
HLA-CDA12
Gene Full Name major histocompatibility complex, class I, F
Gene Summary This gene belongs to the HLA class I heavy chain paralogues. It encodes a non-classical heavy chain that forms a heterodimer with a beta-2 microglobulin light chain, with the heavy chain anchored in the membrane. Unlike most other HLA heavy chains, this molecule is localized in the endoplasmic reticulum and Golgi apparatus, with a small amount present at the cell surface in some cell types. It contains a divergent peptide-binding groove, and is thought to bind a restricted subset of peptides for immune presentation. This gene exhibits few polymorphisms. Multiple transcript variants encoding different isoforms have been found for this gene. These variants lack a coding exon found in transcripts from other HLA paralogues due to an altered splice acceptor site, resulting in a shorter cytoplasmic domain.
Molecular Weight(MW) 39 kDa(Observed:42 kDa)
Cellular Localization Membrane
Database Links
SwissProt ID P30511
Application

WB

Western blot analysis using HLA-F antibody against MCF-7(1) cell lysate.

IHC

Immunohistochemical analysis of paraffin-embedded Human lung cance tissues using HLA-F antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human tonsil tissues using HLA-F antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human renal carcinoma tissues using HLA-F antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human rectal cancer tissues using HLA-F antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human prostate cancer tissues using HLA-F antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human lung cancer tissues using HLA-F antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human breast cancer tissues using HLA-F antibody with DAB staining.
Application Notes WB:1:200-1:2000
IHC:1:100-1:1000
Additional Information
Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer Purified antibody in PBS with 0.05% sodium azide.
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