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Anti-TCF3 antibody-HRP

Catalog Number:OM642471-HRP
Human;Mouse;Rat
WB;IHC
OM642471-HRP
Discount Price
OM642471-HRP-100ul
1~2 Week
100ul
1~2 Week
Product Profile
Product Name Anti-TCF3 antibody-HRP
Antibody Type Primary Antibodies
Immunogen Polypeptide
Conjugation HRP
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WBIHC
WB:1:200-1:2000
IHC:1:100-1:1000
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol TCF3
Gene Synonyms E2A
E47
p75
AGM8
ITF1
VDIR
AGM8A
AGM8B
TCF-3
bHLHb21
Gene Full Name transcription factor 3
Gene Summary This gene encodes a member of the E protein (class I) family of helix-loop-helix transcription factors. E proteins activate transcription by binding to regulatory E-box sequences on target genes as heterodimers or homodimers, and are inhibited by heterodimerization with inhibitor of DNA-binding (class IV) helix-loop-helix proteins. E proteins play a critical role in lymphopoiesis, and the encoded protein is required for B and T lymphocyte development. Deletion of this gene or diminished activity of the encoded protein may play a role in lymphoid malignancies. This gene is also involved in several chromosomal translocations that are associated with lymphoid malignancies including pre-B-cell acute lymphoblastic leukemia (t(1;19), with PBX1), childhood leukemia (t(19;19), with TFPT) and acute leukemia (t(12;19), with ZNF384). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 9.
Molecular Weight(MW) 68 kDa
Cellular Localization Nucleus
Database Links
SwissProt ID P15923
Application

WB

Western blot analysis using TCF3 antibody against HepG2(1),Hela(2),HEK293(3),A549(4) cell lysate.

IHC

Immunohistochemical analysis of paraffin-embedded Human breast cancer tissues using TCF3 antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human Cervical cancer metastasis tissues using TCF3 antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human rectal cancer tissues using TCF3 antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human esophageal cancer tissues using TCF3 antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human colon cancer tissues using TCF3 antibody with DAB staining.
Application Notes WB:1:200-1:2000
IHC:1:100-1:1000
Additional Information
Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer Purified antibody in PBS with 0.05% sodium azide.
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