WB
Western blot analysis using PAX6 antibody against Hela(1),SK-N-SH(2) cell lysate.IHC
Immunohistochemical analysis of paraffin-embedded Human breast cancer tissues using PAX6 antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human renal carcinoma tissues using PAX6 antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human rectal cancer tissues using PAX6 antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human Cervical cancer metastasis tissues using PAX6 antibody with DAB staining.WB
Western blot analysis using PAX6 antibody against Mouse muscle tissue(1).| Product Name | Anti-PAX6 antibody-HRP |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | HRP |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:200-1:2000 IHC:1:100-1:1000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | PAX6 |
|---|---|
| Gene Synonyms | AN AN1 AN2 FVH1 MGDA WAGR ASGD5 D11S812E |
| Gene Full Name | paired box 6 |
| Gene Summary | This gene encodes paired box protein Pax-6, one of many human homologs of the Drosophila melanogaster gene prd. In addition to a conserved paired box domain, a hallmark feature of this gene family, the encoded protein also contains a homeobox domain. Both domains are known to bind DNA and function as regulators of gene transcription. Activity of this protein is key in the development of neural tissues, particularly the eye. This gene is regulated by multiple enhancers located up to hundreds of kilobases distant from this locus. Mutations in this gene or in the enhancer regions can cause ocular disorders such as aniridia and Peter's anomaly. Use of alternate promoters and alternative splicing results in multiple transcript variants encoding different isoforms. Interestingly, inclusion of a particular alternate coding exon has been shown to increase the length of the paired box domain and alter its DNA binding specificity. Consequently, isoforms that carry the shorter paired box domain regulate a different set of genes compared to the isoforms carrying the longer paired box domain. [provided by RefSeq, Mar 2019] |
| Molecular Weight(MW) | 47KD |
| Cellular Localization | Nucleus |
| SwissProt ID | P26367 |
|---|
WB
Western blot analysis using PAX6 antibody against Hela(1),SK-N-SH(2) cell lysate.
IHC
Immunohistochemical analysis of paraffin-embedded Human breast cancer tissues using PAX6 antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human renal carcinoma tissues using PAX6 antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human rectal cancer tissues using PAX6 antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human Cervical cancer metastasis tissues using PAX6 antibody with DAB staining.
WB
Western blot analysis using PAX6 antibody against Mouse muscle tissue(1).| Application Notes | WB:1:200-1:2000 IHC:1:100-1:1000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide. |
