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Anti-STAT5B antibody-HRP

Catalog Number:OM642507-HRP
Human;Mouse;Rat
WB;IHC
OM642507-HRP
Discount Price
OM642507-HRP-100ul
1~2 Week
100ul
1~2 Week
Product Profile
Product Name Anti-STAT5B antibody-HRP
Antibody Type Primary Antibodies
Immunogen Polypeptide
Conjugation HRP
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WBIHC
WB:1:200-1:2000
IHC:1:100-1:1000
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol STAT5B
Gene Synonyms STAT5
GHISID2
Gene Full Name signal transducer and activator of transcription 5B
Gene Summary The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL. [provided by RefSeq, Jul 2008]
Molecular Weight(MW) 90KD
Cellular Localization Cytoplasm, Nucleus
Database Links
SwissProt ID P51692
Application

WB

Western blot analysis using STAT5B antibody against HepG2(1), K562(2) cell lysate.

IHC

Immunohistochemical analysis of paraffin-embedded Human rectal cancer tissues using STAT5B antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human esophageal cancer tissues using STAT5B antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human Cervical cancer metastasis tissues using STAT5B antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human breast cancer tissues using STAT5B antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human breast cancer2 tissues using STAT5B antibody with DAB staining.

WB

Western blot analysis using STAT5B antibody against Mouse brain tissue(1),Mouse testes tissue(2),Mouse heart tissue(3),Mouse liver tissue(4).
Application Notes WB:1:200-1:2000
IHC:1:100-1:1000
Additional Information
Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer Purified antibody in PBS with 0.05% sodium azide.
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