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Anti-CSK antibody-HRP

Catalog Number:OM642521-HRP
Human;Mouse;Rat
WB;IHC
OM642521-HRP
Discount Price
OM642521-HRP-100ul
1~2 Week
100ul
1~2 Week
Product Profile
Product Name Anti-CSK antibody-HRP
Antibody Type Primary Antibodies
Immunogen Polypeptide
Conjugation HRP
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WBIHC
WB:1:200-1:2000
IHC:1:100-1:1000
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol CSK
Gene Synonyms C-Src kinase
Gene Full Name C-terminal Src kinase
Gene Summary The protein encoded by this gene is involved in multiple pathways, including the regulation of Src family kinases. It plays an important role in T-cell activation through its association with the protein encoded by the protein tyrosine phosphatase, non-receptor type 22 (PTPN22) gene. This protein also phosphorylates C-terminal tyrosine residues on multiple substrates, including the protein encoded by the SRC proto-oncogene, non-receptor tyrosine kinase gene. Phosphorylation suppresses the kinase activity of the Src family tyrosine kinases. An intronic polymorphism (rs34933034) in this gene has been found to affect B-cell activation and is associated with systemic lupus erythematosus (SLE). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2017]
Molecular Weight(MW) 51KD
Cellular Localization Cell membrane, Cytoplasm, Membrane
Database Links
SwissProt ID P41240
Application

WB

Western blot analysis using CSK antibody against Cos7(1), A549(2) cell lysate.

IHC

Immunohistochemical analysis of paraffin-embedded Human bladder cancer tissues using CSK antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human lung cancer tissues using CSK antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human Kidney tissues using CSK antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human esophageal cancer tissues using CSK antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human colon cancer tissues using CSK antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human breast cancer tissues using CSK antibody with DAB staining.

WB

Western blot analysis using CSK antibody against Mouse muscle(1) tissue.
Application Notes WB:1:200-1:2000
IHC:1:100-1:1000
Additional Information
Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer Purified antibody in PBS with 0.05% sodium azide.
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