| Gene Symbol |
CRTC3
|
| Gene Synonyms |
2610312F20Rik 6332415K15Rik RGD1309666 TORC-3 TORC3 |
| Gene Full Name |
CREB regulated transcription coactivator 3 |
| Gene Summary |
This gene is a member of the CREB regulated transcription coactivator gene family. This family regulates CREB-dependent gene transcription in a phosphorylation-independent manner and may be selective for cAMP-responsive genes. The protein encoded by this gene may induce mitochondrial biogenesis and attenuate catecholamine signaling in adipose tissue. A translocation event between this gene and Notch coactivator mastermind-like gene 2, which results in a fusion protein, has been reported in mucoepidermoid carcinomas. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Jul 2012] |
| Alternative Names |
CREB-regulated transcription coactivator 3-like TORC-3 transcriptional co-activator transducer of CREB protein 3 transducer of regulated cAMP response element-binding protein (CREB) 3 transducer of regulated cAMP response element-binding protein 3 transducer of regulated CREB protein 3 |
| Molecular Weight(MW) |
67KD(observed:55kDa) |
| Cellular Localization |
Cytoplasm, Nucleus |