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Anti-GHR antibody-HRP

Catalog Number:OM642581-HRP
Human;Mouse;Rat
WB;IHC
OM642581-HRP
Discount Price
OM642581-HRP-100ul
1~2 Week
100ul
1~2 Week
Product Profile
Product Name Anti-GHR antibody-HRP
Antibody Type Primary Antibodies
Immunogen Polypeptide
Conjugation HRP
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WBIHC
WB:1:200-1:2000
IHC:1:100-1:1000
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol GHR
Gene Synonyms GHBP
GHIP
Gene Full Name growth hormone receptor
Gene Summary This gene encodes a member of the type I cytokine receptor family, which is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature. In humans and rabbits, but not rodents, growth hormone binding protein (GHBP) is generated by proteolytic cleavage of the extracellular ligand-binding domain from the mature growth hormone receptor protein. Multiple alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jun 2011]
Molecular Weight(MW) 72KD
Cellular Localization Cell membrane, Membrane, Secreted
Database Links
SwissProt ID P10912
Application

WB

Western blot analysis using GHR antibody against Hek293(1), A431(2) cell lysate.

IHC

Immunohistochemical analysis of paraffin-embedded Human liver cancer tissues using GHR antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human breast cancer tissues using GHR antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human breast cancer tissues using GHR antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human Kidney tissues using GHR antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human liver cancer tissues using GHR antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human lung cancer tissues using GHR antibody with DAB staining.

WB

Western blot analysis using GHR antibody against Mouse heart tissue(1),Mouse muscle tissue(2).
Application Notes WB:1:200-1:2000
IHC:1:100-1:1000
Additional Information
Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer Purified antibody in PBS with 0.05% sodium azide.
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