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Anti-NQO1 antibody-HRP

Catalog Number:OM642618-HRP
Human;Mouse;Rat
WB;IHC
OM642618-HRP
Discount Price
OM642618-HRP-100ul
1~2 Week
100ul
1~2 Week
Product Profile
Product Name Anti-NQO1 antibody-HRP
Antibody Type Primary Antibodies
Immunogen Polypeptide
Conjugation HRP
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WBIHC
WB:1:200-1:2000
IHC:1:100-1:1000
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol NQO1
Gene Synonyms DTD
QR1
DHQU
DIA4
NMOR1
NMORI
Gene Full Name NAD(P)H quinone dehydrogenase 1
Gene Summary This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Molecular Weight(MW) 31KD
Cellular Localization Cytoplasm
Database Links
SwissProt ID P15559
Application

WB

Western blot analysis using NQO1 antibody against NIH3T3(1) cell lysate.

IHC

Immunohistochemical analysis of paraffin-embedded Human breast cancer tissues using NQO1 antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human lung cancer tissues using NQO1 antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human Kidney tissues using NQO1 antibody with DAB staining.
Application Notes WB:1:200-1:2000
IHC:1:100-1:1000
Additional Information
Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer Purified antibody in PBS with 0.05% sodium azide.
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