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Anti-ITGB4 antibody-HRP

Catalog Number:OM642660-HRP
Human;Mouse;Rat
WB;IHC
OM642660-HRP
Discount Price
OM642660-HRP-100ul
1~2 Week
100ul
1~2 Week
Product Profile
Product Name Anti-ITGB4 antibody-HRP
Antibody Type Primary Antibodies
Immunogen Polypeptide
Conjugation HRP
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WBIHC
WB:1:200-1:2000
IHC:1:100-1:1000
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol ITGB4
Gene Synonyms CD104
GP150
JEB5A
JEB5B
Gene Full Name integrin subunit beta 4
Gene Summary ntegrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Molecular Weight(MW) 202KD,107KD
Cellular Localization Plasma membrane
Database Links
SwissProt ID P16144
Application

WB

Western blot analysis using ITGB4 antibody against Cos7(1), Hela(2), Hek293(3), A431(4) cell lysate.

IHC

Immunohistochemical analysis of paraffin-embedded Human breast cancer tissues using ITGB4 antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human lung cancer tissues using ITGB4 antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human prostate cancer tissues using ITGB4 antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human thyroid carcinoma tissues using ITGB4 antibody with DAB staining.
Application Notes WB:1:200-1:2000
IHC:1:100-1:1000
Additional Information
Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer Purified antibody in PBS with 0.05% sodium azide.
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