WB
Western blot analysis using SHP-1 antibody against PC-12(1) cell lysate.IHC
Immunohistochemical analysis of paraffin-embedded Human lung cancer tissues using SHP-1 antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human breast cancer tissues using SHP-1 antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human lymphoid tissues using SHP-1 antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human thyroid carcinoma tissues using SHP-1 antibody with DAB staining.| Product Name | Anti-SHP-1 antibody-HRP |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | HRP |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:200-1:2000 IHC:1:100-1:1000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | PTPN6 |
|---|---|
| Gene Synonyms | PTN6 PTPN6 HCP HCPH SHP1 SHP-1 HPTP1C PTP-1C SHP-1L SH-PTP1 |
| Gene Full Name | protein tyrosine phosphatase non-receptor type 6 |
| Gene Summary | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. N-terminal part of this PTP contains two tandem Src homolog (SH2) domains, which act as protein phospho-tyrosine binding domains, and mediate the interaction of this PTP with its substrates. This PTP is expressed primarily in hematopoietic cells, and functions as an important regulator of multiple signaling pathways in hematopoietic cells. This PTP has been shown to interact with, and dephosphorylate a wide spectrum of phospho-proteins involved in hematopoietic cell signaling. Multiple alternatively spliced variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jul 2008] |
| Molecular Weight(MW) | 67kDa |
| Cellular Localization | Cytoplasm. Nucleus. |
| SwissProt ID | P29350 |
|---|
WB
Western blot analysis using SHP-1 antibody against PC-12(1) cell lysate.
IHC
Immunohistochemical analysis of paraffin-embedded Human lung cancer tissues using SHP-1 antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human breast cancer tissues using SHP-1 antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human lymphoid tissues using SHP-1 antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human thyroid carcinoma tissues using SHP-1 antibody with DAB staining.| Application Notes | WB:1:200-1:2000 IHC:1:100-1:1000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% PC300. |
