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Anti-Catenin-beta antibody-HRP

Catalog Number:OM642910-HRP
Human;Mouse;Rat
WB;IHC
OM642910-HRP
Discount Price
OM642910-HRP-100ul
100ul
Product Profile
Product Name Anti-Catenin-beta antibody-HRP
Antibody Type Primary Antibodies
Immunogen Polypeptide
Conjugation HRP
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WBIHC
WB:1:200-1:2000
IHC:1:100-1:1000
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol CTNNB1
Gene Synonyms CTNNB1
EVR7
CTNNB
MRD19
NEDSDV
armadillo
Gene Full Name catenin beta 1
Gene Summary The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2016]
Molecular Weight(MW) 85KDa
Cellular Localization Cell junction, Cell membrane, Cell projection, Cytoplasm, Cytoskeleton, Membrane, Nucleus, Synapse
Database Links
SwissProt ID P35222
Application

IHC

Immunohistochemical analysis of paraffin-embedded Human breast cancer tissues using Catenin-beta antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human liver tissues using Catenin-beta antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human lung cancer tissues using Catenin-beta antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human prostate cancer tissues using Catenin-beta antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human renal carcinoma tissues using Catenin-beta antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human stomach cancer tissues using Catenin-beta antibody with DAB staining.

WB

Western blot analysis using Catenin-beta antibody against MCF-7(1) cell lysate.

WB

Western blot analysis using Catenin-beta antibody against Mouse stomach(1) tissue.
Application Notes WB:1:200-1:2000
IHC:1:100-1:1000
Additional Information
Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer Purified antibody in PBS with 0.05% PC300.
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