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Anti-Bak antibody-HRP

Catalog Number:OM642924-HRP
Human;Mouse;Rat
WB;IHC
OM642924-HRP
Discount Price
OM642924-HRP-100ul
100ul
Product Profile
Product Name Anti-Bak antibody-HRP
Antibody Type Primary Antibodies
Immunogen Polypeptide
Conjugation HRP
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WBIHC
WB:1:200-1:2000
IHC:1:100-1:1000
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol BAK1
Gene Synonyms BAK
CDN1
BCL2L7
BAK-LIKE
Gene Full Name BCL2 antagonist/killer 1
Gene Summary The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress. [provided by RefSeq, Jul 2008]
Molecular Weight(MW) 23kDa(Observed:30 kDa)
Cellular Localization Mitochondrion membrane
Database Links
SwissProt ID Q16611
Application

WB

Western blot analysis using Bak antibody against HepG2(1) cell lysate.

IHC

Immunohistochemical analysis of paraffin-embedded Human thyroid carcinoma tissues using Bak antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human breast cancer tissues using Bak antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human lung cancer tissues using Bak antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human stomach cancer tissues using Bak antibody with DAB staining.

WB

Western blot analysis using Bak antibody against Mouse serum(1),Mouse brain(2) tissue.
Application Notes WB:1:200-1:2000
IHC:1:100-1:1000
Additional Information
Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer Purified antibody in PBS with 0.05% PC300.
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