C57BL/6 splenocytes were cultured for 4 days in the presence of LPS, stained with CD45R/B220 APC, fixed and permeabilized using Transcription Factor Buffer, then stained with Blimp-1 PE (left) or Rat IgG2a, κ PE Isotype control (right)
Amino acids 255-395 from mouse Blimp-1 fused with GST.
Key Feature
Clonality
monoclonal
Isotype
IgG2a,k
Host Species
Rat
Tested Applications
FC
Species Reactivity
Mouse
Concentration
0.2mg/ml
Purification
Affinity purified
Target Information
Gene Symbol
Prdm1
Gene Synonyms
Blimp1 Blimp-1 PRDI-BF1 ZNFPR1A1 b2b1765Clo
Gene Full Name
PR domain containing 1, with ZNF domain
Gene Summary
Enables histone methyltransferase binding activity; promoter-specific chromatin binding activity; and transcription cis-regulatory region binding activity. Involved in gene expression; peptidyl-arginine methylation; and regulation of lymphocyte differentiation. Acts upstream of or within several processes, including circulatory system development; eye morphogenesis; and regulation of gene expression. Located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; embryo mesenchyme; genitourinary system; retina; and skin. Used to study systemic lupus erythematosus. Human ortholog(s) of this gene implicated in hepatocellular carcinoma and lung adenocarcinoma. Orthologous to human PRDM1 (PR/SET domain 1). [provided by Alliance of Genome Resources, Mar 2025]
Application
FC
C57BL/6 splenocytes were cultured for 4 days in the presence of LPS, stained with CD45R/B220 APC, fixed and permeabilized using Transcription Factor Buffer, then stained with Blimp-1 PE (left) or Rat IgG2a, κ PE Isotype control (right)
Additional Information
Form
Liquid
Storage Instructions
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.