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CD45 Rabbit mAb (AbFluor 488)
Catalog Number:OM644135
Human
IF-P
OM644135
Discount Price
OM644135-100ul
100ul
OM644135-50ul
50ul
OM644135-20ul
20ul
Product Profile
Product Name CD45 Rabbit mAb (AbFluor 488)
Antibody Type Primary Antibodies
Key Feature
Clonality monoclonal
Isotype IgG
Host Species Rabbit
Tested Applications IF-P
IF-P:1:50-1:200
Species Reactivity Human
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol PTPRC
Gene Synonyms LCA
LY5
B220
CD45
L-CA
T200
CD45R
GP180
IMD105
Gene Full Name protein tyrosine phosphatase receptor type C
Gene Summary The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jun 2012]
Molecular Weight(MW) 147kDa
Cellular Localization Membrane.
Application

IF-P

Immunofluorescence analysis of human tonsil. 1,primary Antibody was diluted at 1:100(4~C overnight).
Application Notes IF-P:1:50-1:200
Additional Information
Form Liquid
Storage Instructions -15°C to -25°C/1 year(Do not lower than -25°C)
Storage Buffer PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
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