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Anti-Neu-N (Fox 3) Antibody

Catalog Number:OM644503
Human;Mouse;Rat
IF-P;IHC;WB
OM644503
Discount Price
OM644503-50ul
50ul
Product Profile
Product Name Anti-Neu-N (Fox 3) Antibody
Antibody Type Primary Antibodies
Immunogen N-terminal 100 amino acids of human FOX3 expressed in and purified from E. coli
Key Feature
Clonality Polyclonal
Isotype IgY
Host Species Chicken
Tested Applications IF-PIHCWB
WB:1:250-1:500
IHC:1:2000-1:4000
IF-P:1:2000-1:4000
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol RBFOX3
Gene Synonyms FOX3
NEUN
FOX-3
HRNBP3
Gene Full Name RNA binding fox-1 homolog 3
Gene Summary This gene encodes a member of the RNA-binding FOX protein family which is involved in the regulation of alternative splicing of pre-mRNA. The protein has an N-terminal proline-rich region, an RNA recognition motif (RRM) domain, and a C-terminal alanine-rich region. This gene produces the neuronal nuclei (NeuN) antigen that has been widely used as a marker for post-mitotic neurons. This gene has its highest expression in the central nervous system and plays a prominent role in neural tissue development and regulation of adult brain function. Mutations in this gene have been associated with numerous neurological disorders. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, May 2017]
Alternative Names RNA binding protein fox-1 homolog 3
Fox-1 homolog C
Neuronal nuclei antigen
NeuN antigen)
Molecular Weight(MW) 48kDa
Cellular Localization Cytoplasm,Nucleus.
Application

IF-P

Representative section of formalin fixed, paraffin-embedded rat brain cerebellum region showing cells stained by anti-NeuN (Rbfox3) antibody. The sections were stained with Aves Labs antiNeuN polyclonal antibody (visualized in green). The stained sections were mounted with Antibodies Incorporated Fluoroshield with DAPI and DABCO mounting medium. DAPI nuclear stain (blue) shows cell nuclei.

IF-P

Representative section of formalin fixed, paraffinembedded rat brain hippocampus region showing cells stained by anti-NeuN (Rbfox3) antibody. The sections were stained with Aves Labs anti-NeuN polyclonal antibody (visualized in green). The stained sections were mounted with Antibodies Incorporated Fluoroshield with DAPI and DABCO mounting medium. DAPI nuclear stain (blue) shows cell nuclei.
Application Notes WB:1:250-1:500
IHC:1:2000-1:4000
IF-P:1:2000-1:4000
Additional Information
Form Liquid
Storage Instructions Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.
Storage Buffer Concentrated IgY preparation plus 0.02% NaN3
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