This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008]
Molecular Weight(MW)
50 kDa
Cellular Localization
Cytoplasm,Intermediate filament
Application
WB
Western blot analysis of GFAP in mouse brain , rat brain lysates and using GFAP Goat pAb.
IF-P
Immunofluorescence analysis of GFAP(Green) in mouse brain tissue using GFAP Goat pAb,and DAPI(Blue)
Application Notes
WB:1:500-1:1000 IF-P:100-1:300
Additional Information
Form
Liquid
Storage Instructions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Storage Buffer
Liquid in PBS, 50% glycerol, 0.05% Proclin 300, 0.08%BSA.