| Product Name | CD68 Monoclonal Antibody, FITC |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide. |
| Conjugation | FITC |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Host Species | Mouse |
| Tested Applications | IF |
| IF:1:100 FC:Assay-dependent |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | CD68 |
|---|---|
| Gene Synonyms | GP110 LAMP4 SCARD1 |
| Gene Full Name | CD68 molecule |
| Gene Summary | This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms. [provided by RefSeq, Jul 2008] |
| Alternative Names | 110kda transmembrane glycoprotein CD68 antigen macrophage antigen CD68 scavenger receptor class D member 1 unnamed protein product GP110 LAMP4 SCARD1 |
| Molecular Weight(MW) | 110 kDa |
| Cellular Localization | Cell membrane,Endosome,Lysosome,membrane. |
| SwissProt ID | P34810 |
|---|
| Application Notes | IF:1:100 FC:Assay-dependent |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | 4°C, store in dark, DO NOT FREEZE! |
| Storage Buffer | PBS with 1% BSA. |
