ICC/IF
Immunofluorescence analysis of Hela cells using SETDB1 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.| Product Name | Anti-SETDB1 antibody-AF488 |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | AF488 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IFFC |
| IF:1:50-1:200 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | SETDB1 |
|---|---|
| Gene Synonyms | SETB1 ESET KG1T KMT1E KIAA0067 H3-K9-HMTase4 SETDB1 |
| Gene Full Name | SET domain bifurcated histone lysine methyltransferase 1 |
| Gene Summary | This gene encodes a histone methyltransferase which regulates histone methylation, gene silencing, and transcriptional repression. This gene has been identified as a target for treatment in Huntington Disease, given that gene silencing and transcription dysfunction likely play a role in the disease pathogenesis. Alternatively spliced transcript variants of this gene have been described.[provided by RefSeq, Jun 2011] |
| Molecular Weight(MW) | 180 kDa（Observed:120 kDa） |
| Source | Rabbit |
| Cellular Localization | Chromosome, Cytoplasm, Nucleus |
| SwissProt ID | Q15047 |
|---|
ICC/IF
Immunofluorescence analysis of Hela cells using SETDB1 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.| Application Notes | IF:1:50-1:200 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide. |
