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Anti-p38 antibody-poly-HRP

Catalog Number:OM650068-poly-HRP
Human;Mouse;Rat
WB;IHC
OM650068-poly-HRP
Discount Price
OM650068-poly-HRP-100ul
1~2 Week
100ul
1~2 Week
Product Profile
Product Name Anti-p38 antibody-poly-HRP
Antibody Type Primary Antibodies
Immunogen Polypeptide
Conjugation poly-HRP
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WBIHC
WB:1:200-1:2000
IHC:1:100-1:1000
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol MAPK14
Gene Synonyms MK14
RK
p38
CSBP
EXIP
Mxi2
CSBP1
CSBP2
CSPB1
PRKM14
PRKM15
SAPK2A
p38ALPHA
Gene Full Name mitogen-activated protein kinase 14
Gene Summary The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
Molecular Weight(MW) 41 KDa
Source Rabbit
Cellular Localization Cytoplasm, Nucleus
Database Links
SwissProt ID Q16539
Application

WB

Western blot analysis using p38 antibody against A549(1) cell lysate.

IHC

Immunohistochemical analysis of paraffin-embedded Human breast cancer tissues using p38 antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human cervical cancer tissues using p38 antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human breast cancer tissues using p38 antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human colon cancer tissues using p38 antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human lung cancer tissues using p38 antibody with DAB staining.

WB

Western blot analysis using p38 antibody against Mouse brain(1) lysate.
Application Notes WB:1:200-1:2000
IHC:1:100-1:1000
Additional Information
Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer Purified antibody in PBS with 0.05% sodium azide.
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