WB
Western blot analysis using ALIX antibody against U251(1) cell lysate.IHC
Immunohistochemical analysis of paraffin-embedded Human lung cancer tissues using ALIX antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human breast cancer tissues using ALIX antibody with DAB staining. .IHC
Immunohistochemical analysis of paraffin-embedded Human colon cancer tissues using ALIX antibody with DAB staining. .IHC
Immunohistochemical analysis of paraffin-embedded Human renal carcinoma tissues using ALIX antibody with DAB staining. .IHC
Immunohistochemical analysis of paraffin-embedded Human stomach cancer tissues using ALIX antibody with DAB staining. .| Product Name | Anti-ALIX antibody-HRP |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | HRP |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:200-1:2000 IHC:1:100-1:1000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | PDCD6IP |
|---|---|
| Gene Synonyms | PDC6I PDCD6IP AIP1 ALIX HP95 DRIP4 |
| Gene Full Name | programmed cell death 6 interacting protein |
| Gene Summary | This gene encodes a protein that functions within the ESCRT pathway in the abscission stage of cytokinesis, in intralumenal endosomal vesicle formation, and in enveloped virus budding. Studies using mouse cells have shown that overexpression of this protein can block apoptosis. In addition, the product of this gene binds to the product of the PDCD6 gene, a protein required for apoptosis, in a calcium-dependent manner. This gene product also binds to endophilins, proteins that regulate membrane shape during endocytosis. Overexpression of this gene product and endophilins results in cytoplasmic vacuolization, which may be partly responsible for the protection against cell death. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. Related pseudogenes have been identified on chromosome 15. [provided by RefSeq, Jan 2012] |
| Molecular Weight(MW) | 96 KDa |
| Source | Rabbit |
| Cellular Localization | Cell junction, Cytoplasm, Cytoskeleton, Secreted, Tight junction |
| SwissProt ID | Q8WUM4 |
|---|
WB
Western blot analysis using ALIX antibody against U251(1) cell lysate.
IHC
Immunohistochemical analysis of paraffin-embedded Human lung cancer tissues using ALIX antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human breast cancer tissues using ALIX antibody with DAB staining. .
IHC
Immunohistochemical analysis of paraffin-embedded Human colon cancer tissues using ALIX antibody with DAB staining. .
IHC
Immunohistochemical analysis of paraffin-embedded Human renal carcinoma tissues using ALIX antibody with DAB staining. .
IHC
Immunohistochemical analysis of paraffin-embedded Human stomach cancer tissues using ALIX antibody with DAB staining. .| Application Notes | WB:1:200-1:2000 IHC:1:100-1:1000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide. |
