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Anti-Fbx32 antibody-HRP

Catalog Number:OM650128-HRP
Human;Mouse;Rat
WB;IHC
OM650128-HRP
Discount Price
OM650128-HRP-100ul
1~2 Week
100ul
1~2 Week
Product Profile
Product Name Anti-Fbx32 antibody-HRP
Antibody Type Primary Antibodies
Immunogen Polypeptide
Conjugation HRP
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WBIHC
WB:1:200-1:2000
IHC:1:100-1:1000
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol FBXO32
Gene Synonyms Fbx32
MAFbx
Gene Full Name F-box protein 32
Gene Summary This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2011]
Molecular Weight(MW) 42 kDa, 25kDa
Source Rabbit
Cellular Localization Cytoplasm, Nucleus
Database Links
SwissProt ID Q969P5
Application

WB

Western blot analysis using Fbx32 antibody against A549(1),Cos-7(2) cell lysate.

IHC

Immunohistochemical analysis of paraffin-embedded Human breast cancer tissues using Fbx32 antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human cardiac muscle tissues using Fbx32 antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human lung cancer tissues using Fbx32 antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human renal carcinoma tissues using Fbx32 antibody with DAB staining.
Application Notes WB:1:200-1:2000
IHC:1:100-1:1000
Additional Information
Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer Purified antibody in PBS with 0.05% sodium azide.
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