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Anti-PKC epsilon antibody-HRP

Catalog Number:OM650172-HRP
Human;Mouse;Rat
WB;IHC
OM650172-HRP
Discount Price
OM650172-HRP-100ul
1~2 Week
100ul
1~2 Week
Product Profile
Product Name Anti-PKC epsilon antibody-HRP
Antibody Type Primary Antibodies
Immunogen Polypeptide
Conjugation HRP
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WBIHC
WB:1:200-1:2000
IHC:1:100-1:1000
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol PRKCE
Gene Synonyms KPCE
PKCE
nPKC-epsilon
Gene Full Name protein kinase C epsilon
Gene Summary Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been shown to be involved in many different cellular functions, such as neuron channel activation, apoptosis, cardioprotection from ischemia, heat shock response, as well as insulin exocytosis. Knockout studies in mice suggest that this kinase is important for lipopolysaccharide (LPS)-mediated signaling in activated macrophages and may also play a role in controlling anxiety-like behavior. [provided by RefSeq, Jul 2008]
Molecular Weight(MW) 84kDa
Cellular Localization Cell membrane, Cytoplasm, Cytoskeleton, Membrane, Nucleus
Database Links
SwissProt ID Q02156
Application

IHC

Immunohistochemical analysis of paraffin-embedded Human breast cancer tissues using PKC epsilon antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human lung cancer tissues using PKC epsilon antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human cervical cancer tissues using PKC epsilon antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human lung cancer tissues using PKC epsilon antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human rectal cancer tissues using PKC epsilon antibody with DAB staining.

WB

Western blot analysis using PKC epsilon antibody against Mouse stomach(1),Rat serum (2) tissue.
Application Notes WB:1:200-1:2000
IHC:1:100-1:1000
Additional Information
Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer Purified antibody in PBS with 0.05% sodium azide.
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