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Anti-STAT5a antibody-HRP

Catalog Number:OM650188-HRP
Human;Mouse;Rat
WB;IHC
OM650188-HRP
Discount Price
OM650188-HRP-100ul
1~2 Week
100ul
1~2 Week
Product Profile
Product Name Anti-STAT5a antibody-HRP
Antibody Type Primary Antibodies
Immunogen Polypeptide
Conjugation HRP
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WBIHC
WB:1:200-1:2000
IHC:1:100-1:1000
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol STAT5A
Gene Synonyms MGF
STAT5
Gene Full Name signal transducer and activator of transcription 5A
Gene Summary The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells. Alternatively spliced transcript variants have been found for this gene.
Molecular Weight(MW) 91 kDa
Cellular Localization Cytoplasm, Nucleus
Database Links
SwissProt ID P42229
Application

WB

Western blot analysis using STAT5a antibody against K562(1) cell lysate.

IHC

Immunohistochemical analysis of paraffin-embedded Human lung cancer tissues using STAT5a antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human breast cancer tissues using STAT5a antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human lung cancer tissues using STAT5a antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human ovarian cancer tissues using STAT5a antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human prostate cancer tissues using STAT5a antibody with DAB staining.
Application Notes WB:1:200-1:2000
IHC:1:100-1:1000
Additional Information
Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer Purified antibody in PBS with 0.05% sodium azide.
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