| Gene Symbol |
AKT2
|
| Gene Synonyms |
PKBB
PRKBB
HIHGHH
PKBBETA
RAC-BETA |
| Gene Full Name |
AKT serine/threonine kinase 2 |
| Gene Summary |
This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains, which is involved in signaling pathways. The gene serves as an oncogene in the tumorigenesis of cancer cells For example, its overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins, and has also been implicated in insulin signaling. |
| Molecular Weight(MW) |
56 kDa |
| Cellular Localization |
Cell membrane, Cytoplasm, Endosome, Membrane, Nucleus |
