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Anti-CRTC2 antibody-HRP

Catalog Number:OM650324-HRP
Human;Mouse;Rat
IHC
OM650324-HRP
Discount Price
OM650324-HRP-100ul
1~2 Week
100ul
1~2 Week
Product Profile
Product Name Anti-CRTC2 antibody-HRP
Antibody Type Primary Antibodies
Immunogen Polypeptide
Conjugation HRP
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications IHC
IHC:1:100-1:1000
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol CRTC2
Gene Synonyms TORC2
TORC-2
Gene Full Name CREB regulated transcription coactivator 2
Gene Summary This gene encodes a member of the transducers of regulated cAMP response element-binding protein activity family of transcription coactivators. These proteins promote the transcription of genes targeted by the cAMP response element-binding protein, and therefore play an important role in many cellular processes. Under basal conditions the encoded protein is phosphorylated by AMP-activated protein kinase or the salt-inducible kinases and is sequestered in the cytoplasm. Upon activation by elevated cAMP or calcium, the encoded protein translocates to the nucleus and increases target gene expression. Single nucleotide polymorphisms in this gene may increase the risk of type 2 diabetes. A pseudogene of this gene is located on the long arm of chromosome 5. [provided by RefSeq, Dec 2010]
Molecular Weight(MW) 73KD
Cellular Localization Cytoplasm, Nucleus
Database Links
SwissProt ID Q53ET0
Application

IHC

Immunohistochemical analysis of paraffin-embedded Human liver cancer tissues using CRTC2 antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human breast cancer tissues using CRTC2 antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human cervical cancer tissues using CRTC2 antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human prostate cancer tissues using CRTC2 antibody with DAB staining.
Application Notes IHC:1:100-1:1000
Additional Information
Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer Purified antibody in PBS with 0.05% sodium azide.
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