| Gene Symbol |
RAB21
|
| Gene Synonyms |
KIAA0118 |
| Gene Full Name |
RAB21, member RAS oncogene family |
| Gene Summary |
This gene belongs to the Rab family of monomeric GTPases, which are involved in the control of cellular membrane traffic. The encoded protein plays a role in the targeted trafficking of integrins via its association with integrin alpha tails. As a consequence, the encoded protein is involved in the regulation of cell adhesion and migration. Expression of this gene is associated with a poor prognosis for glioma patients. This gene is downregulated by the tumor suppressor miR-200b, and miRNA-200b is itself downregulated in glioma tissues. [provided by RefSeq, Nov 2015] |
| Molecular Weight(MW) |
24kDa（Observed:38 kDa） |
| Cellular Localization |
Cell projection, Cytoplasmic vesicle, Endoplasmic reticulum, Endosome, Golgi apparatus, Membrane |
