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Anti-SFTPC antibody-HRP

Catalog Number:OM660020-HRP
Human;Mouse;Rat
WB;IHC
OM660020-HRP
Discount Price
OM660020-HRP-100ul
1~2 Week
100ul
1~2 Week
Product Profile
Product Name Anti-SFTPC antibody-HRP
Antibody Type Primary Antibodies
Immunogen Polypeptide
Conjugation HRP
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WBIHC
WB:1:200-1:2000
IHC:1:100-1:1000
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol SFTPC
Gene Synonyms SP5
SP-C
PSP-C
SFTP2
SMDP2
BRICD6
Gene Full Name surfactant protein C
Gene Summary This gene encodes the pulmonary-associated surfactant protein C (SPC), an extremely hydrophobic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90% lipids and 10% proteins which include plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. Multiple mutations in this gene have been identified, which cause pulmonary surfactant metabolism dysfunction type 2, also called pulmonary alveolar proteinosis due to surfactant protein C deficiency, and are associated with interstitial lung disease in older infants, children, and adults. Alternatively spliced transcript variants encoding different protein isoforms have been identified.[provided by RefSeq, Feb 2010]
Molecular Weight(MW) 21kDa
Cellular Localization Secreted, Surface film
Database Links
SwissProt ID P11686
Application

WB

Western blot analysis using SFTPC antibody against Mcf-7(1) cell lysate.

WB

Western blot analysis using SFTPC antibody against Cos-7(1),A431(2),Mcf-7(3),A549(4) cell lysate.

IHC

Immunohistochemical analysis of paraffin-embedded Human lung tissues using SFTPC antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human lung cancer tissues using SFTPC antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human lung tissues using SFTPC antibody with DAB staining.
Application Notes WB:1:200-1:2000
IHC:1:100-1:1000
Additional Information
Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer Purified antibody in PBS with 0.05% sodium azide.
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