WB
Western blot analysis using PRKCG antibody against Mouse brain(1) lysate.WB
Western blot analysis using PRKCG antibody against Hela(1),Hepg2(2),Cos-7(3),Mcf-7(4),A549(5) cell lysate and Mouse kidney(6) lysate.IHC
Immunohistochemical analysis of paraffin-embedded Human esophageal cancer tissues using PRKCG antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human Kidney tissues using PRKCG antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human liver cancer tissues using PRKCG antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human lung cancer tissues using PRKCG antibody with DAB staining.| Product Name | Anti-PRKCG antibody-poly-HRP |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | poly-HRP |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:200-1:2000 IHC:1:100-1:1000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | PRKCG |
|---|---|
| Gene Synonyms | PKCC PKCG SCA14 PKCI(3) PKCgamma PKC-gamma |
| Gene Full Name | protein kinase C gamma |
| Gene Summary | Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase is expressed solely in the brain and spinal cord and its localization is restricted to neurons. It has been demonstrated that several neuronal functions, including long term potentiation (LTP) and long term depression (LTD), specifically require this kinase. Knockout studies in mice also suggest that this kinase may be involved in neuropathic pain development. Defects in this protein have been associated with neurodegenerative disorder spinocerebellar ataxia-14 (SCA14). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015] |
| Molecular Weight(MW) | 78kDa |
| Cellular Localization | Cell junction, Cell membrane, Cell projection, Cytoplasm, Membrane, Synapse, Synaptosome |
| SwissProt ID | P05129 |
|---|
WB
Western blot analysis using PRKCG antibody against Mouse brain(1) lysate.
WB
Western blot analysis using PRKCG antibody against Hela(1),Hepg2(2),Cos-7(3),Mcf-7(4),A549(5) cell lysate and Mouse kidney(6) lysate.
IHC
Immunohistochemical analysis of paraffin-embedded Human esophageal cancer tissues using PRKCG antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human Kidney tissues using PRKCG antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human liver cancer tissues using PRKCG antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human lung cancer tissues using PRKCG antibody with DAB staining.| Application Notes | WB:1:200-1:2000 IHC:1:100-1:1000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide. |
