| Gene Symbol |
PIK3CG
|
| Gene Synonyms |
PI3K PIK3 IMD97 PI3CG PI3Kgamma p110gamma p120-PI3K |
| Gene Full Name |
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma |
| Gene Summary |
Phosphoinositide 3-kinases (PI3Ks) phosphorylate inositol lipids and are involved in the immune response. The protein encoded by this gene is a class I catalytic subunit of PI3K. Like other class I catalytic subunits (p110-alpha p110-beta, and p110-delta), the encoded protein binds a p85 regulatory subunit to form PI3K. This gene is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jun 2015] |
| Molecular Weight(MW) |
126kDa |
| Cellular Localization |
Cell membrane, Cytoplasm, Cytoskeleton, Membrane |