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Anti-GAD2 antibody-HRP

Catalog Number:OM660229-HRP
Human;Mouse;Rat
WB
OM660229-HRP
Discount Price
OM660229-HRP-100ul
100ul
Product Profile
Product Name Anti-GAD2 antibody-HRP
Antibody Type Primary Antibodies
Immunogen Polypeptide
Conjugation HRP
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
WB:1:200-1:2000
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol GAD2
Gene Synonyms GAD65
DCE2
Gene Full Name glutamate decarboxylase 2
Gene Summary This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Oct 2008]
Molecular Weight(MW) 65kDa
Cellular Localization Cytoplasm, cytosol, Cytoplasmic vesicle, Presynaptic cell membrane, Golgi apparatus membrane
Database Links
SwissProt ID Q05329
Application

WB

Western blot analysis using GAD2 antibody against Cos-7(1) cell lysate.
Application Notes WB:1:200-1:2000
Additional Information
Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer Purified antibody in PBS with 0.05% sodium azide.
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