| Gene Symbol |
TREX1
|
| Gene Synonyms |
CRV AGS1 DRN3 HERNS RVCLS |
| Gene Full Name |
three prime repair exonuclease 1 |
| Gene Summary |
This gene encodes a nuclear protein with 3' exonuclease activity. The encoded protein may play a role in DNA repair and serve as a proofreading function for DNA polymerase. Mutations in this gene result in Aicardi-Goutieres syndrome, chilblain lupus, Cree encephalitis, and other diseases of the immune system. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2012] |
| Molecular Weight(MW) |
33kDa(observed:38kDa) |
| Cellular Localization |
Cytoplasm, Endoplasmic reticulum, Membrane, Nucleus |