IHC
Immunohistochemical analysis of paraffin-embedded Human bladder cancer tissues using Neurofibromin 2 antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human Kidney tissues using Neurofibromin 2 antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human lung cancer tissues using Neurofibromin 2 antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human thyroid carcinoma tissues using Neurofibromin 2 antibody with DAB staining.WB
Western blot analysis using Neurofibromin 2 antibody against Hepg2(1),A549(2),Huvec(3),Cos-7(4),P19(5),B16(6),C2C12(7),K562(8),Jurkat(9),MFC(10),Nih3t3(11),T24(12)cellWB
Western blot analysis using Neurofibromin 2 antibody against Mouse intestine(1),Mouse heart(2),Rat spleen(3),Rat serum(4),Rat lung(5) tissue.| Product Name | Anti-Neurofibromin 2 antibody-HRP |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | HRP |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:200-1:2000 IHC:1:100-1:1000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | NF2 |
|---|---|
| Gene Synonyms | ACN SCH BANF SWNV merlin-1 |
| Gene Full Name | NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor |
| Gene Summary | This gene encodes a protein that is similar to some members of the ERM (ezrin, radixin, moesin) family of proteins that link cytoskeletal components with proteins in the cell membrane. The encoded protein is involved in regulation of contact-dependent inhibition of cell proliferation and functions in cell-cell adhesion and transmembrane signaling. The encoded protein has been shown to interact with cell-surface proteins, proteins involved in cytoskeletal dynamics, and proteins involved in regulating ion transport. Disruption of this protein's function has been implicated in tumorigenesis and metastasis. Mutations in this gene are associated with neurofibromatosis type II which is characterized by nervous system and skin tumors and ocular abnormalities. [provided by RefSeq, May 2022] |
| Molecular Weight(MW) | 70kDa(observed:50-55kDa) |
| Cellular Localization | Cell membrane, Cell projection, Cytoplasm, Cytoskeleton, Membrane, Nucleus. |
| SwissProt ID | P35240 |
|---|
IHC
Immunohistochemical analysis of paraffin-embedded Human bladder cancer tissues using Neurofibromin 2 antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human Kidney tissues using Neurofibromin 2 antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human lung cancer tissues using Neurofibromin 2 antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human thyroid carcinoma tissues using Neurofibromin 2 antibody with DAB staining.
WB
Western blot analysis using Neurofibromin 2 antibody against Hepg2(1),A549(2),Huvec(3),Cos-7(4),P19(5),B16(6),C2C12(7),K562(8),Jurkat(9),MFC(10),Nih3t3(11),T24(12)cell
WB
Western blot analysis using Neurofibromin 2 antibody against Mouse intestine(1),Mouse heart(2),Rat spleen(3),Rat serum(4),Rat lung(5) tissue.| Application Notes | WB:1:200-1:2000 IHC:1:100-1:1000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide. |
