The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Alternative Names
activator protein 1 DKFZp686C0818 FBJ murine osteosarcoma viral oncogene homolog B FBJ osteosarcoma oncogene B fos b FOSB FosB proto-oncogene AP-1 trancription factor subunit G0/G1 switch regulatory protein 3 GOS3 is human homolog of mouse FOSB gene MGC42291 oncogene FOS-B osteosarcoma oncoprotein B FosB protein fosB transcription factor AP-1 subunit FosB