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Anti-p300 antibody-HRP

Catalog Number:OM660384-HRP
Human;Mouse;Rat
WB;IHC
OM660384-HRP
Discount Price
OM660384-HRP-100ul
1~2 Week
100ul
1~2 Week
Product Profile
Product Name Anti-p300 antibody-HRP
Antibody Type Primary Antibodies
Immunogen Polypeptide
Conjugation HRP
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WBIHC
WB:1:200-1:2000
IHC:1:100-1:1000
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol EP300
Gene Synonyms EP300
P300
Histone acetyltransferase p300
p300 HAT
E1A-associated protein p300
Gene Full Name EP300 lysine acetyltransferase
Gene Summary This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer. [provided by RefSeq, Jul 2008]
Molecular Weight(MW) 264kDa
Source Rabbit
Cellular Localization Cytoplasm, Nucleus
Database Links
SwissProt ID Q09472
Application

IHC

Immunohistochemical analysis of paraffin-embedded Human breast cancer tissues using P300 antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human cervical cancer tissues using P300 antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human ovarian cancer tissues using P300 antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human prostate cancer tissues using P300 antibody with DAB staining.

WB

Western blot analysis using p300 antibody against Hela(1),Cos-7(2),K562(3)cell.
Application Notes WB:1:200-1:2000
IHC:1:100-1:1000
Additional Information
Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer Purified antibody in PBS with 0.05% sodium azide.
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