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Anti-FTO antibody-poly-HRP

Catalog Number:OM660411-poly-HRP
Human;Mouse;Rat
WB;IHC
OM660411-poly-HRP
Discount Price
OM660411-poly-HRP-100ul
1~2 Week
100ul
1~2 Week
Product Profile
Product Name Anti-FTO antibody-poly-HRP
Antibody Type Primary Antibodies
Immunogen Polypeptide
Conjugation poly-HRP
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WBIHC
WB:1:200-1:2000
IHC:1:100-1:1000
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol FTO
Gene Synonyms FTO
KIAA1752
Alpha-ketoglutarate-dependent dioxygenase FTO
Fat mass and obesity-associated protein
Gene Full Name FTO alpha-ketoglutarate dependent dioxygenase
Gene Summary This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes. [provided by RefSeq, Jul 2011]
Molecular Weight(MW) 58kDa(observed:70kDa)
Source Rabbit
Cellular Localization Nucleus, Cytoplasm
Database Links
SwissProt ID Q9C0B1
Application

IHC

Immunohistochemical analysis of paraffin-embedded Human breast cancer tissues using FTO antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human esophageal cancer tissues using FTO antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human lung cancer tissues using FTO antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human ovarian cancer tissues using FTO antibody with DAB staining.

WB

Western blot analysis using FTO antibody against T24(1),Raji(2) cell.

WB

Western blot analysis using FTO antibody against Mouse brain(1),Mouse intestine(2),Mouse testes(3),Mouse heart(4),Mouse stomach(5),Mouse liver(6) tissue.
Application Notes WB:1:200-1:2000
IHC:1:100-1:1000
Additional Information
Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer Purified antibody in PBS with 0.05% sodium azide.
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