ICC/IF
Immunofluorescence analysis of U251 cells using IP3 Receptor antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.| Product Name | Anti-IP3 Receptor antibody-AF488 |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | AF488 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IFFC |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | ITPR1 |
|---|---|
| Gene Synonyms | ITPR1 INSP3R1 ITPR1 IP3R 1 Type 1 InsP3 receptor |
| Gene Full Name | inositol 1,4,5-trisphosphate receptor type 1 |
| Gene Summary | This gene encodes an intracellular receptor for inositol 1,4,5-trisphosphate. Upon stimulation by inositol 1,4,5-trisphosphate, this receptor mediates calcium release from the endoplasmic reticulum. Mutations in this gene cause spinocerebellar ataxia type 15, a disease associated with an heterogeneous group of cerebellar disorders. Multiple transcript variants have been identified for this gene. [provided by RefSeq, Nov 2009] |
| Molecular Weight(MW) | 314kDa |
| Source | Rabbit |
| Cellular Localization | Endoplasmic reticulum membrane, secretory vesicle membrane, perinuclear region |
| SwissProt ID | Q14643 |
|---|
ICC/IF
Immunofluorescence analysis of U251 cells using IP3 Receptor antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide. |
